---
title: CTMS Updates And The Audit Trail
description: Learn how the CTMS interface displays on Protocol Audit Trails
---

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3. [CTMS Interface](https://vestigohelp.mccreadiegroup.com/en/knowledgebase/vestigo-interfaces-and-integrations?hsLang=en#ctms-interface)

September 25, 2026

# CTMS Updates And The Audit Trail

### CTMS Updates

For protocols linked to CTMS, updates from the CTMS to Vestigo will occur every 2-3 hours, or when the “Update from CTMS” link is selected on the Protocol Identifier grid, Contact’s tab, or Patient/Subjects tab of a Protocol.The interface will automatically update Protocol Contacts, Protocol Identifiers, Protocol Title, Lead Sponsor, Status, Phase, and Protocol Design.

#### Participant Enrollment

Participant and Participant Enrollment records are never updated by the interface. All changes must be confirmed by a user. 

#### Sponsor Updates

If primary sponsor information is changed in CTMS, it will update Vestigo.  Vestigo can only   
accommodate one sponsor name.  

 

### Vestigo Audit Trail

All changes are captured in the Audit Trail and attributed to the Interface as the user who made the change. If a user triggers an update, they will be attributed as the modifying user in the Audit Trail. Audit Trail updates are visible on the Protocol Audit Trail, and in the Address Book for contacts that are updated. 

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